MYC, MAX, and small cell lung cancer.

نویسندگان

  • Charles M Rudin
  • J T Poirier
چکیده

SUMMARY In this issue of Cancer Discovery, Romero and colleagues identify somatic mutations and deletions of MAX, and also define what seem to be mutually exclusive alterations in MYC family members and other MYC-associated factors in small cell lung cancer. Taken together, these data highlight the importance of MYC signaling in small cell lung cancer and suggest possible avenues for therapeutic intervention.

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عنوان ژورنال:
  • Cancer discovery

دوره 4 3  شماره 

صفحات  -

تاریخ انتشار 2014